Detroit

Detroit is the starting location of Human Revolution and the hometown of its protagonist, Adam Jensen. It is split between pro- and anti-augmentation groups, and rioting on its streets was shown in the E3 2010 trailer.

Plot
Jonathan Jacques-Belletête, Human Revolution's art director, has said:

 The interesting thing about Detroit is that it looks quite a bit like contemporary Detroit; this is really all about anticipating what the world will be in 2027. We've designed stuff like objects which recharge electrical cars - we've invented them, and looked at where billboard technologies are going. So it's a lot like today's Detroit, with those added layers grafted over it. Plus there are those interesting and very modern-looking buildings. It's sad for Detroit, because it was one of the hearts of America for quite a while because of the automobile industry. It's not really happening anymore - all those factories are abandoned. The idea is that with Sarif Industries, the company that Adam Jensen works for, David Sarif wanted to rejuvenate Detroit through the cybernetic industry. Just like the car industry did in the 20th century. That's why, in the game, you actually go to visit those manufacturing plants. Sarif bought those abandoned car plants and renovated them for super hi-tech cybernetics. He's sending a message to the city and the world: "I'm from Detroit, I love this city, I'm giving it a new breath."