The Shadow of Omega is an eBook in Deus Ex: Human Revolution. It can be found in Omega Ranch, in room B-22 of Bio-Mech Labs.
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Chapter Four: The 2018 Accident
Omega Ranch was a massive undertaking, a highly-secure site with multiple labs and research departments, along with support structures and an accommodation complex. In 2009 the Disease Control Initiative opened their doors to the world's doctors, but the facility was dogged by technical issues, staffing problems and underfunding.
The pressures on the WHO staff at the isolated facility grew and finally, in 2018, the worst-case scenario came to pass. A breach in containment led to the explosive spread of a modified variant of the H5N1 avian flu virus, which swept across Malaysia, killing tens of thousands of people.
The exact details of the cause of the outbreak are unclear, although some conspiracists have insisted that the event was deliberately triggered by clandestine groups - perhaps as an attempt to destabilize the region. The epidemic would have lasting effects on Malaysia.